Table 1.

Five genotypes of breast cancer

Genotypes	Characteristics	Other characteristics*
Basal-like subtype	ER (-), PR (-), HER2 (-)	CK5/6 (+), EGFR (+), BRCA1 mutation, 82% TP53 mutation [2]
HER2 subtype	HER2 (+), ER (-), PR (-)	GRB7 (+), TRAP100 [3] high expression, 71% TP53 mutation
Luminal A subtype	ER (+) or PR (+), HER2 (-)	GATA3 (+), FOXA1 [4] high expression
Luminal B subtype	ER (+) or PR (+), HER2 (+)	CGH (+), LAPTMB4 (+), NSEP-1F high expression, 40% TP53 mutation
Normal breast-like subtype	ER (-), PR (-), HER2 (-)	CK5/6 (-), EGFR (-), 33% TP53 mutation

^*In our study, we detected CK5/6, EGFR, TP53 by IHC to identify the tissue belonging to Basal-like subtype or Normal breast-like subtype.