Table 2.
Hepatic lipid indices, concentrations of SOD, MDA and GSH-Px in 10% liver homogenate
Parameter | Group C | Group M | Group E1 | Group E2 |
---|---|---|---|---|
TG (mmol/L) | 0.62 ± 0.27a | 2.24 ± 0.45b | 1.84 ± 0.45b,c | 1.46 ± 0.67c |
TC (mmol/L) | 0.70 ± 0.18a | 2.41 ± 0.51b | 2.60 ± 1.02b | 1.94 ± 0.82b |
MDA (nmol/mgprot) | 2.18 ± 0.56a | 2.34 ± 0.31a | 1.86 ± 0.22a | 0.99 ± 0.30b |
SOD (U/mgprot) | 32.99 ± 4.88a | 31.11 ± 2.86a | 33.57 ± 5.03a | 44.28 ± 7.40b |
GSH-Px (U/mgprot) | 642 ± 108a | 330 ± 68b | 341 ± 41b | 448 ± 68c |
The concentration of liver homogenate was diluted to one-tenth with normal saline. Group C were treated with standard restricted diet (3/4 amount compared with ad libitum, n = 5); Group M were given high fat liquid diet ad libitum (n = 5); Group E1 were treated with high fat liquid diet ad libitum and MTBITC by gavage (9 mg/kg body weight per day, n = 5); Group E2 were treated with high fat liquid diet ad libitum and MTBITC by gavage (18 mg/kg body weight per day, n = 5); All the rats were orally treated with soybean oil (35 g/L diet) as vehicle. TG, triglyceride; TC, total cholesterol; MDA, malondialdehyde; SOD, superoxide dismutase; GSH-Px, glutathione-peroxidase; MTBITC, 4-(Methylthio)-3-butenyl isothiocyanate. Values are expressed as mean ± SD (n = 5).
Values in a line with a different letter are significantly different at P < 0.05.
Values in a line with a different letter are significantly different at P < 0.05.
Values in a line with a different letter are significantly different at P < 0.05.