Table 3.
Multivariate analyses of the risk of ≥ grade-2 radiation-induced pneumonitis (RP)
| Risk factor | No RP n (%) | RP n (%) | P-value | OR (95% CI) | β value |
|---|---|---|---|---|---|
| Smoker | 39 (46.4) | 38 (66.7) | |||
| Nonsmoker | 45 (53.6) | 19 (33.3) | 0.028 | 0.42 (0.20-0.91) | -0.86 |
| Lung cancer | 49 (58.3) | 49 (84.2) | |||
| ESCC | 20 (23.8) | 7 (12.3) | 0.067a | 0.37 (0.13-1.07) | -0.97 |
| Mediastinal tumor | 15 (17.9) | 2 (3.5) | 0.015a | 0.14 (0.03-0.63) | -1.95 |
| Sequential chemotherapy | 76 (90.5) | 42 (73.7) | |||
| Concurrent chemotherapy | 8 (9.5) | 15 (26.3) | 0.037 | 2.97 (1.07-8.26) | 1.09 |
| Total radiation dose ≤ 53 Gy | 44 (52.4) | 21 (36.8) | |||
| Total radiation dose > 53 Gy | 40 (47.6) | 36 (63.2) | 0.027 | 2.44 (1.11-5.35) | 0.89 |
OR, odds ratio; CI, confidence interval; ESCC, esophageal squamous cell carcinoma;
a
Compared with lung cancer cases.