Table 4.

Risk of SCLC associated with RAD52 rs7963551 A > C genotypes by age, sex and smoking status

Variable	RAD52 rs7963551 A > C
	CC1	CA+AA1	OR (95% CI)2	P
Age (year)
≤ 57	190/328	65/171	0.63 (0.43-0.91)	0.015
> 57	205/345	60/196	0.48 (0.33-0.70)	1.4×10-4
Sex
Male	295/494	104/280	0.59 (0.44-0.79)	3.8×10-4
Female	100/179	21/87	0.43 (0.23-0.79)	0.007
Smoking status
No	84/472	30/236	0.73 (0.47-1.14)	0.161
Yes	311/201	95/131	0.49 (0.35-0.67)	1.0×10-5
Clinical stage
Limited	226/673	69/367	0.53 (0.38-0.73)	1.0×10-4
Extensive	169/673	56/367	0.55 (0.39-0.78)	0.001

Abbreviations: SCLC, small cell lung cancer; OR, odds ratio; CI, confidence interval.

¹Number of case patients with genotype/number of control subjects with genotype.

²Data were calculated by logistic regression, adjusted for sex, age, and smoking status, where it was appropriate.