Table 1.
Characteristics of 11 articles included in our study that reported on using miR-223 as diagnostic biomarkers of various cancers
| Author/Year | Country/ethnicity | Sample | Cancer type | Case/control | AUC | Sensitivity | Specificity | Quality score (QUADAS) |
|---|---|---|---|---|---|---|---|---|
| Zhang/2010 | China/Asian | serum | ESCC | 149/100 | 0.911 | 83.2% | 83.0% | 12 |
| Zhu/2011 | China/Asian | bone marrow | Leukemia | 147/147 | 0.853 | 76.62% | 90.0% | 12 |
| Li/2012 | China/Asian | plasma | GC | 70/70 | 0.9089 | 84.29% | 88.57% | 12 |
| Xu/2012 | China/Asian | serum | HCC | 101/89 | 73.55% | 85.54% | 12 | |
| Sara/2012 | Canada/Caucasian | serum | OC | 30/26 | 0.81 | 96.2% | 60.0% | 12 |
| Jia/2013 | China/Asian | serum | EEC | 26/22 | 0.727 | 57.89% | 95.08% | 12 |
| Kim/2013 | Korea/Asian | serum | GC | 31/15 | 0.750 | 80.11% | 69.04% | 11 |
| Geng/2014 | China/Asian | plasma | NSCLC | 126/60 | 0.96 | 87.0% | 86.0% | 12 |
| Zheng/2014 | China/Asian | serum | CRC | 160/94 | 0.890 | 83.32% | 84.57% | 12 |
| Wang/2014 | China/Asian | serum | GC | 50/47 | 0.85 | 81.0% | 78.0% | 12 |
| Wu/2014 | China/Asian | serum | ESCC | 63/63 | 0.772 | 63.13% | 81.11% | 12 |