Table 1. Cox proportional hazards regression model showing the association of variables with disease-free survival.
Variable | Crude analysis | Multivariable analysis | ||||
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Prognostic factor | HR | 95 % CI | P value | HR | 95 % CI | P value |
Factors selected | ||||||
Male | 1.82 | 0.96–3.44 | 0.007 | 3.71 | 1.66–8.30 | 0.001 |
Size | ||||||
<5 cm | Ref | – | – | Ref | – | – |
5–10 cm | 2.26 | 1.01–5.05 | 0.05 | 1.90 | 0.78–4.62 | 0.16 |
≥10cm | 6.23 | 2.88–13.47 | <0.001 | 3.14 | 1.20–8.19 | 0.02 |
Site | ||||||
Gastric | Ref | – | – | Ref | – | – |
Non-gastric | 2.04 | 1.18–3.51 | 0.01 | 1.87 | 0.90–3.89 | 0.09 |
Mitotic rate group | ||||||
≤5 mitoses/50 HPF | Ref | – | – | Ref | – | – |
6–10 mitoses/50 HPF | 2.64 | 0.99–7.04 | 0.05 | 1.57 | 0.54–4.57 | 0.41 |
>10 mitoses/50 HPF | 7.66 | 3.65–16.06 | <0.001 | 8.56 | 3.15–23.25 | <0.001 |
Factors not selected | ||||||
Age, year | 1.02 | 0.99–1.05 | 0.27 | – | – | – |
Tumor rupture | 2.97 | 0.41–21.79 | 0.28 | – | – | – |
R1 Margin | 0.67 | 0.09–4.92 | 0.70 | – | – | – |