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. Author manuscript; available in PMC: 2015 Nov 25.
Published in final edited form as: Angiogenesis. 2015 Jun 20;18(4):477–488. doi: 10.1007/s10456-015-9475-4

Fig. 1.

Fig. 1

KSHV infection causes the Warburg effect in endothelial cells. a HUVECs were infected with rKSHV.219 and selected with puromycin. Expression of GFP and LANA1 (indirect immunofluorescence) of cells infected with live rKSHV.219 (KSHV) or UV-inactivated rKSHV.219 (IN-KSHV) is shown. Nuclei are visualized with DAPI staining. b Extracellular lactate concentration, relative oxygen consumption, ratio of mitochondrial DNA and mitochondrial biomass of parental HUVEC, KSHV, and IN-KSHV cell lines (calculated as described in “Materials and methods” section)