Table 6.

Interaction between apolipoprotein-E ε4 and disease severity on working memory

	B	SE B	t	P	95% CI		Partial η2
					Lower	Upper
Step 1a
Age	−0.02	0.01	−3.49	0.001	−0.04	−0.01	0.05
Ethnicityb	0.34	0.11	3.14	0.002	0.13	0.55	0.04
Cognitive reserve	0.03	0.004	5.79	<0.001	0.02	0.03	0.12
Sexc	0.02	0.15	0.11	0.91	−0.27	0.30	0.00
Step 2							0.00
Disease severityd	−0.09	0.11	−0.86	0.39	−0.30	0.12	0.00
ε4 allelee	0.01	0.11	0.12	0.91	−0.21	0.23	0.00
Step 3
ε4 allele × disease severity	−0.48	0.22	−2.16	0.03	−0.93	−0.04	0.02

Notes:

^aR2 = 0.21 for step 1, ΔR2 = 0.002 for step 2 (P = 0.69), ΔR2 = 0.01 for step 3 (P = 0.03);

^breference group is ethnic minority;

^creference group is male;

^dreference group is CD4+ ≥ 200;

^ereference group is ε4–.

Abbreviations: CI, confidence interval; SE, standard error.