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. 2015 Aug 14;15:336. doi: 10.1186/s12879-015-1081-y

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© Hofstra et al. 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Changes over Time. Changes in relative abundances over time of the genera Haemophilus, Neisseria, Staphylococus and the bacterial species H. parainfluenzae, Neisseria subflava and Staphylococcus aureus. Strong trends towards increases in the relative abundance of the bacterial genera Haemophilus (raw p-value = 0.0041, false discovery rate (FDR) 0.178) and Neisseria (raw p-value = 0.0049, FDR 0.178) were observed, as well as a weaker trend towards increases of the bacterial genus Staphylococcus (raw p = value 0.0749, FRD 0.518). Analysis on species level revealed trends toward increases of Haemophilus parainfluenzae (raw p-value = 0.0098 FDR = 0.12), Neisseria subflava (raw p-value = 0.012 FDR = 0.12), Staphylococcus aureus (raw p-value = 0.0856 FDR = 0.245) during infection. Plots represent mean ± SEM