FIG 4 .

Relative abundance of the predicted KEGG orthologous groups (KOs) in the fecal (A) and salivary (B) samples from the clindamycin group plotted against the samples from the KI placebo group per individual time point. Error lines indicate standard deviations. No significant differences were observed in saliva, while in feces, 3 KOs at 1 week post-antibiotic treatment and 512 of the 4,606 predicted KOs at 1 month post-antibiotic treatment were significantly different in their proportions from the placebo group (P < 0.005, Welch’s t test, Welch’s inverted confidence interval method, and Storey FDR correction for multiple comparisons).