. Author manuscript; available in PMC: 2015 Nov 25.

Published in final edited form as: Neurosurg Clin N Am. 2014 Oct;25(4):671–692. doi: 10.1016/j.nec.2014.07.009

Table 1.

Review of the studies investigating the clinical role for septal stimulation for the treatment of pain

Study, Year	Study Type	Pain Type	Total-(Implanted)-Success	Electrode and Stimulation Parameters	Side Effects
Heath & Mickle,¹⁵ 1960	CS	RA/CP	6-NFS	4 Strand, silver-plated copper wire, plastic insulation, silver ball tip	Rapid speech, alert, acute relief of pain
Ervin et al,¹⁶ 1969	CS	CP	NFS	NFS	Mild euphoria, acute relief of pain
Gol,¹⁷ 1967	CS	CP/BP	6-1	Heavy, single-lead electrode, 6 terminal, silver ball tip, 2000–5000 c/s, 0–12 V	More cheerful, alert
Schvarcz,¹⁸ 1985	CS	CP/DP	10-10-6	Standard DBS electrode	Feeling of warmth, well-being, relaxation
Schvarcz,¹⁹ 1993	CS	CP/DP	19-19-12	Bipolar or tetrapolar electrode	Feeling of warmth, well-being

Abbreviations: BP, back pain; CP, cancer pain; CS, case series; NFS, not further specified; RA, rheumatoid arthritis; V, volts.