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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Free Radic Biol Med. 2015 Jun 27;88(0 0):108–146. doi: 10.1016/j.freeradbiomed.2015.06.021

Fig. 3.

Fig. 3

Domain structure of human Nrf2. The relative positions of the Neh domains of transcription factor Nrf2 are shown. The degrons responsible for targeting of Nrf2 protein by Keap1 and β-TrCP for proteasomal degradation are indicated above the domains, and the region of Nrf2 through which it is inhibited by RXRα is indicated. The numbering of amino acids is based on the human sequence and is shown below the cartoon.