Table 1.
Summary of selected interstitial CBUS devices, their design features, performance evaluations and clinical utilizations.
CBUS Device | General Design Features | Performance | Site-Specific Evaluations | Clinical Utilization |
---|---|---|---|---|
Interstitial: sectored tubular arrays | Multiple sectored tubular transducer array; 6 -8 MHz; 10 – 15 mm segments; 1.5 – 2.4 mm OD; Sector-based angular control; integratedcatheter or internal cooling | Lesion dimensions 15-20 mm radial, 10 – 40 mm length; Ablation and HT; MRTI, CT, US, Fluoroscopy guidance | in vivo canine brain [10, 37] and prostate [36], porcine liver [31] ovine [21] and rabbit spine [22] | Prostate and cervix hyperthermia with HDR brachytherapy [38] |
Interstitial: multi-faced | 7-sided catheter assembly w/ array of 1 mm × 1mm transducers; 6 MHz; 8 mm active length; OD = 3.2 mm; angular control through power activation on each face; external cooling sheath | Radial treatment depth > 15 mm; MR-compatible with MRTI in 1.5 T | Brain [11] | |
Interstitial & Intraductal rotating planar | 3.8-4 mm OD catheter, 8-10 mm length × 2.8-3.0 mm planar transducer segment, ∼5 or 10 MHz, motorized rotation; integrated cooling sheath | ∼20 mm radial × 8 mm length penetration, rotation for angular control; endoscopic intraluminal or interstitial; fluoroscopy or US guidance. | Porcine biliary tract [84, 85] and liver [30, 84] | Bile duct carcinoma [125] |
Interstitial: dual-mode | Dual-mode linear array, 32 rect. Elements, 2.3 × 49 mm2; 3.1 or 4.8 MHz; motorized rotational control; balloon cooling | Lesion dimensions ∼ 18 mm radial,∼ 5 mm wide, and ∼ 15 mm length; Dual-mode with US B-mode imaging | in vivo rabbit liver [14, 15] | |
Interstitial: dual-mode w/ mechanical rotation | Dual-mode linear array; 5 rect. elements, 3 × 20 mm2, 5 - 6 MHz, cylindrical focus ∼ 14 mm; motorized rotational control; balloon cooling | Lesion dimensions 19 mm depth, ∼9 mm wide; dual-mode with US therapy with all 5 elements, B-mode imaging with central transducer | Porcine liver in vivo [18] |