Table 1. Selected Population Characteristics by Genome-Wide Association Study Stage and Case-Control Status Among Women of European Ancestry.
GWAS Stage I | GWAS Stage II | |||
---|---|---|---|---|
Cases | Controls | Cases | Controls | |
Total N | 2,695 | 2,776 | 681 | 1,091 |
Mean age (SD) | 62.3 (8.3) | 60.8 (9.7) | 59.7 (9.3) | 59.9 (10.5) |
Mean BMI (SD) | 29.7 (7.6) | 26.1 (5.3) | 32.4 (8.4) | 27.8 (5.6) |
Diabetes (%) | 11.7 | 4.7 | 12.3 | 6.9 |
Ever used hormone therapy (%) | 48.2 | 46.4 | 37.6 | 42.5 |
Mean BMI GRS (SD) | 91.8 (6.2) | 91.4 (6.2) | 91.9 (6.1) | 91.4 (6.2) |
Abbreviations: BMI, body mass index; GRS, genetic risk score; GWAS, genome-wide association study; N, sample size; SD standard deviation.