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. 2015 Nov 25;10(11):e0142804. doi: 10.1371/journal.pone.0142804

Table 1. Placebo attitudes and ways in which physicians would describe placebos to patients.

Question % of respondents 1
Canada US 2 P-value
I have prescribed or administered a placebo in the following situation(s):
After all clinically indicated treatment possibilities were exhausted 11 11 NS
After "unjustified" demand for medication 8 15 χ2(1) = 5.1 (P = 0.024)
To placate or calm a patient 13 18 NS
To control pain (including in the context of patient-controlled analgesia) 5 6 NS
As a diagnostic tool (e.g., to distinguish between psychogenic and organic causes of symptoms) 10 4 χ2(1) = 6.5 (P = 0.011)
As a supplemental treatment 14 18 NS
For non-specific complaints 12 13 NS
To stop patients from complaining 4 6 NS
If I were to prescribe a placebo, I would tell the patient that:
It is a medication 4 19 χ2(1) = 22.5 (P < 0.0001)
It is a placebo 11 4 χ2(1) = 7.4 (P = 0.007)
It is medicine with no specific effect 6 9 NS
It is a substance that may help and will not harm 35 34 NS
Other 5 33 χ2(1) = 51.6 (P < 0.0001)
The following statement(s) best describe(s) my position on the use of placebos outside of research:
The use of placebos should be categorically prohibited. 9 12 NS
The use of placebos may be permitted if research supports its efficacy. 44 46 NS
The use of placebos may be permitted if the experience of colleagues supports it. 9 9 NS
The use of placebos may be permitted after notifying the patient that he/she is receiving a placebo. 31 21 χ2(1) = 5.7 (P = 0.017)
The use of placebos may be permitted if I anticipate that it will be of benefit to the patient. 37 31 NS

1 Sums may exceed 100% due to acceptance of multiple responses.

2 reported in Sherman et al., 2008

NS = non-significant, as determined by chi-square test