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Trees were constructed using the closest homologs to S. agnetis toxin proteins from BLASTp searches of refseq proteins from S. hyicus, S.chromgenes, S. pseudintermedius and S. aureus. Tress are for Superantigen-like protein homologs (Panel A), beta hemolysin (Panel B), and exfoliative toxin A (Panel C). The S. agnetis ortholog are prefixed with the ORF number from S1 Table. Details of the alignment strategy are in Materials and Methods.
