Fig 3. Principle coordinate analysis (PCoA) of (A) Unweighted (P = 0.0003) and (B) Weighted (P = 0.06) UniFrac distances, an OTU based unsupervised measure of beta-diversity in fecal samples collected before induction of colitis.

Fecal samples clustered according to the treatment. The clustering was further influenced by the mother especially in the unweighted analysis (P = 0.001). The P values were determined using PERMANOVA. 10 mice per group. ControlM1 and ControlM2 shows mice in the control group but from two different mothers; ATBm1 and ATBm2 shows mice in the ATB (antibiotic) group but from two different mothers.