Skip to main content
. 2015 Nov 25;10(11):e0142536. doi: 10.1371/journal.pone.0142536

Fig 7. Impacts of dextran sulfate sodium (DSS) and antepartum antibiotics on colitis induction and disease severity.

Fig 7

DSS caused a significant increase in the disease activity index (A), macroscopic score (B), and histology score (C). Antepartum antibiotic exposure increased histological score in DSS-induced colitis as assessed by appearance of colon (D) in mice without antibiotic exposure (Control-DSS) (a), and in mice exposed to antibiotics (ATB-DSS) (b). Antepartum antibiotic exposure increased IL-6 (E), but did not effect IL-1β (F), and reduced C-reactive protein (CRP) (G). Values are shown as mean ± SEM. 10 mice per group.