. Author manuscript; available in PMC: 2016 Sep 1.

Published in final edited form as: Exp Eye Res. 2015 Jul 2;138:134–144. doi: 10.1016/j.exer.2015.06.027

Table 2.

Relative Aβ₄₀ and Aβ₄₂ in sNEP-treated eyes of 2–3-month 5XFAD mice.

sNEP dose (μg)	Post-treatment period	Relative level^*
sNEP dose (μg)	Post-treatment period	Aβ₄₀	Aβ₄₂
10	2 hr	0.11 ± 0.09 (p = 0.01)	0.98 ± 0.10 (p = 0.86)
0.004	1 day	0.38 ± 0.01 (p < 0.001)	0.91 ± 0.27 (p = 0.77)
5	1 day	0.06 ± 0.01 (p < 0.001)	0.53 ± 0.06 (p = 0.02)
10	1 day	0.01 ± 0.01 (p < 0.001)	0.58 ± 0.36 (p = 0.37)
10	3 days	0.03 ± 0.02 (p < 0.001)	0.50 ± 0.03 (p = 0.004)
10	1 month	0.15 ± 0.02 (p < 0.001)	0.45 ± 0.02 (p = 0.001)

Mean ± SEM of results from ≥ 2 animals. The p value accompanying each entry is the result of two-tailed Student’s t-test analysis testing whether the value differs from unity.