Extended Data Figure 4. Representative densities of the three reconstructions of GlyR. Densities are sharpened using RELION unless indicated.
The densities in each panel are for the str-, gly/ivm-, gly-, and unsharpened gly-bound states, respectively, from left to right. a, Representative densities of the β-sheets in ECD, contoured at 8 σ. b, Densities of Cys-loop and the M2-M3 loop, contoured at 7 σ. c, Densities of helices M1 and M2, contoured at 7 σ. d, Densities of M3 and M4, contoured at 7 σ. e, Densities of −2′Pro, contoured at 7 σ except for the gly-bound state (6.5 σ). f, Densities of 9′Leu, contoured at 6.0 σ except for the gly-bound state (5.0 σ).
