Figure 4.
(A) Ezetimibe does not influence mRNA levels of two classical ER members, the Erα and Erβ genes, and a new ER member, the Gpr30 gene in the liver. (B) Ezetimibe treatment significantly reduces mRNA levels of Npc1l1 in the small intestine. See text for further description of other genes. *P<0.01 and **P<0.001, compared with E2-treated OVX mice receiving no ezetimibe and fed the lithogenic diet for 8 weeks.