Table 2.
Age, gender and genetic defects in our 6 patients with Jacobsen syndrome
| Patient number | Age (years) | Gender | Genetic abnormalities | Clinical findings |
|---|---|---|---|---|
| 1 | 24 | M | 11q- (45, x, ish der) (11) t (y;11) (p11.2;q24.1) (wcpyt)2 | Recurrent otitis, sinusitis, upper and lower respiratory tract infections |
| 2 | 35 | F | Deletion 11q (q23.3 – qter) | No recurrent infections |
| 3 | 14 | F | Deletion 11q (q.24.1-qter) | Recurrent otitis, upper and lower respiratory tract infections |
| 4 | 14 | M | Deletion 11q 14.2 – 11q 22.2 | Recurrent upper and lower respiratory tract infections |
| 5 | 6 | F | Deletion 11q (q23.3 – qter) | Recurrent otitis, sinusitis, upper and lower respiratory tract infections |
| 6 | 10 | F | Deletion 11q (q23.3 – qter) | Recurrent otitis, sinusitis, upper and lower respiratory tract infections |
This table shows the age, gender (F = female, M = male) and confirmed genetic abnormalities of the 6 Dutch patients with Jacobsen syndrome studied