We found an increased risk of sudden cardiac death associated with current use of domperidone compared with non-use of study medications. |
Certain subgroups of domperidone users, e.g. users of higher daily doses and those older than 60 years of age, may be at higher risk than others. The higher risk is confined to the first 16 days of continuous treatment. |
The risk of sudden cardiac death appears to be increased in patients receiving metoclopramide and was an unexpected finding. |