Fig. 4.

Correlation between the background incidence of events and the contribution of each system to signal detection. The background incidences of the events (per 100,000 person-years), estimated from exploring and understanding adverse drug reactions (EU-ADR) data, pooled across all databases, were bullous eruption = 4.2, pancreatitis = 21.4, upper gastrointestinal bleeding = 82.2, hip fracture = 117.7 and acute myocardial infarction = 153.7. ‘Identified signals’ refer to signals proven to be known adverse drug reactions