Fig. 4.

Diseases of Immune Dysregulation. AD Autosomal Dominant inheritance, ALPS Autoimmune lymphoproliferative syndrome, AR Autosomal Recessive inheritance, CD Cluster of Differentiation, CMF Flow cytometry available, CSF Cerebrospinal fluid, CTL Cytotoxic T-Lymphocyte, EBV Epstein-Barr Virus, GOF Gain-of-function, HLH Hemophagocytic lymphohistiocytosis, HSM Hepatosplenomegaly, IBD Inflammatory bowel disease, IFNγ Interferon gamma, Ig Immunoglobulin, IL interleukin, Inflam Inflammation, NK Natural Killer, NKT Natural Killer T cell, T T lymphocyte, XL X-Linked inheritance