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. 2015 Nov 26;6:1317. doi: 10.3389/fmicb.2015.01317

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Copyright © 2015 Nami, Haghshenas, Haghshenas, Abdullah and Yari Khosroushahi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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4′,6-diamidino-2-phenylindole (DAPI) staining and flow cytometric analysis of treated/untreated HeLa cancer cells. (a,b) Untreated and treated DAPI-stained cells; (c,d) flow cytometric analysis of untreated and treated cells with 50 μg/mL E. lactis secretion metabolites after 24 h incubation. Dots with Annexin V^-/PI⁺ (Q1), Annexin V⁺/PI⁺ (Q2), Annexin V⁺/PI^- (Q3), and Annexin V^-/PI^- (Q4) and feature represent necrotic, late apoptotic, early apoptotic, and viable intact cells, respectively.