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. Author manuscript; available in PMC: 2016 Nov 5.
Published in final edited form as: Mol Cell. 2015 Oct 22;60(3):475–486. doi: 10.1016/j.molcel.2015.09.013

Figure 3. Ligand-induced changes of the human 80S pre-translocation complex.

Figure 3

Population FRET histograms showing the impact of (A) deacylated-tRNAArg (B) cycloheximide (CHX) and (C) harringtonine (HTN) on the equilibrium distribution of FRET states in the human 80S PRE complex bearing Cy3- and Cy5-labeled P- and A-site tRNAs, respectively. See also Figure S3.