Plasma M-CSF in AAV and healthy controls. M-CSF levels discriminate between patients with AAV and healthy controls. M-CSF levels are higher in patients with active renal disease. SEM: standard error of mean. ⁎p<0.001, significantly different from controls; §: p=0.014, p=0.019, p=0.002 and p<0.001, significantly different from patients with active disease without renal involvement, from patients in remission with a history of renal involvement, from patients in remission without a history of renal involvement and from healthy controls respectively.