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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: J Am Acad Child Adolesc Psychiatry. 2015 Oct 8;54(12):999–1007.e4. doi: 10.1016/j.jaac.2015.09.016

Table 1.

Discontinuation Rates by Reason and Medicationa

Total (24.7%; 69/279) Risperidone (15.7%; 14/89) Lithium (32.2%; 29/90) Divalproex Sodium (26.0%; 26/100)
Reasons for Discontinuation, n (%)
Changed Mind 37/69 (53.6) 8/14 (57.8) 15/29 (51.7) 14/26 (53.8)
Side effects 15/69 (21.7) 3/14 (21.4) 8/29 (27.6) 4/26 (15.4)
Worsening of Symptoms 7/69 (10.1) 0/14 (0) 4/29 (13.8) 3/26 (11.5)
Psychiatric Hospitalization 4/69 (5.8) 1/14 (7.1) 1/29 (3.4) 2/26 (7.7)
Geographical relocation 1/69 (1.4) 0/14 (0) 0/29 (0) 1/26 (3.8)
Onset of severe medical illness 1/69 (1.4) 0/14 (0) 0/29 (0) 1/26 (3.8)
Weight/BMI increase 1/69 (1.4) 1/14 (7.1) 0/29 (0) 0/26 (0)
Other 3/69 (4.3) 1/14 (7.1) 1/29 (3.4) 1/26 (3.8)

Note: BMI = body mass index

a

Adapted from Geller et al.16, eTable 1.