Table 2B.

Logistic Regression Model of Clinical Global Impression-Bipolar (CGI-BP) Depression Improvement

	Dropouts coded as no improvement			Last observation carried forward			Completers only, n=216
	OR	95%CI for OR	p value	OR	95%CI for OR	p value	OR	95%CI for OR	p value
RISP vs. LI	2.13	1.09, 4.18	0.027	2.03	1.01, 4.08	0.046	0.80	0.34, 1.85	0.596
VAL vs. LI	0.83	0.43, 1.58	0.565	1.08	0.56, 2.09	0.820	0.59	0.26, 1.34	0.209
RISP vs. VAL	2.58	1.32, 5.05	0.006	1.88	0.95, 3.74	0.070	1.34	0.59, 3.02	0.482
white vs. other	0.72	0.26, 2.01	0.534	0.81	0.29, 2.28	0.695	0.74	0.22, 2.54	0.634
black vs. other	0.37	0.12, 1.16	0.089	0.56	0.18, 1.8	0.334	1.11	0.27, 4.57	0.886
age at baseline (per year)	1.04	0.94, 1.15	0.429	1.05	0.94, 1.16	0.389	1.11	0.98, 1.26	0.101
KMRS score	0.99	0.96, 1.03	0.649	0.94	0.91, 0.98	0.001	0.87	0.82, 0.92	<0.0001
CDRS at baseline	1.02	0.99, 1.05	0.225	1.03	1.00, 1.06	0.097	1.03	0.99, 1.06	0.180
Clinical Site (Children's National Med Center as reference)	1.00			1.00			1.00
Johns Hopkins Medical Inst.	0.15	0.06, 0.35	<0.0001	0.15	0.06, 0.38	<0.0001	0.17	0.06, 0.51	0.002
University of Pittsburgh.	1.01	0.4, 2.51	0.990	0.83	0.31, 2.21	0.705	0.76	0.24, 2.37	0.637
University of Texas	0.13	0.05, 0.31	<0.0001	0.16	0.06, 0.42	<0.0001	0.34	0.11, 1.08	0.067
Washington University	0.18	0.07, 0.42	<0.0001	0.13	0.05, 0.33	<0.0001	0.16	0.05, 0.47	0.001

Note: Boldface type represents statistically significant data. CDRS = Children's Depression Rating Scale; KMRS = Kiddie Mania Rating Scale; LI = lithium carbonate; RISP = risperidone; VAL = divalproex sodium.