Fig. 6.

Coefficients from the PCA Regression model. This figure shows bar plots of the coefficient estimates from the univariate and multivariate mixed-effects models with the biomarker as an outcome. The results from the univariate model are shown in blue, and the results from the multivariate model are shown in green. Asterisks indicate significance at the 5% level. In both the univariate and multivariate models, disease-modifying therapy, steroids, and age were found to be significant.