Table 5. List of PCSK2 SNPs associated with type 2 diabetes or glucose homeostatic parameters according to published data or GWAS database.

SNP name [Ref. No]	Chromosome Position	Genetic variants	Phenotype	Pvalue	Ethnicity
CA repeat in intron 2 polymorphism [ref. 28]	Chromosome 20	(CA)15–21	type 2 diabetes	0.0068 [(CA)21]	Japanese
rs2208203 [ref. 45]	17,272,003	C/T	reduced insulin secretion and lower fasting glucagon levels in non-diabetic individuals	1.3 × 10−6 (corrected insulin response during OGTT) 1.6 × 10−7 (disposition index) 0.0048 (fasting glucagon levels)	Finland and Sweden
rs2021785 [ref. 27]	17,370,063	C/T	Type 2 diabetes	0.00014	African Americans
rs1609659 [ref. 27]	17,170,735	A/G		0.028
rs4814597 [ref. 27]	17,159,633	G/A		0.039
rs2269023 [ref. 27]	17,381,079	T/C		0.043
rs2021785 [ref. 29]	17,370,063	C/T	Type 2 diabetes	0.0335	Han Chinese
rs2206447 [ref. 46]	17,330,737	C/T	Type 2 diabetes	0.007631	Caucasian
rs6080705 [ref. 46]	17,401,598	C/A	HOMA-beta	0.008588
			HOMA-IR	0.02582
			FINS	0.01508