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. 2015 Oct-Dec;7(4):367–377. doi: 10.4103/0974-8490.159569

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Histopathological study of paw tissue (H and E, ×400). Group I - normal rats (a). Group II - arthritis, which shows severe edema formation and severe cells infiltration and vascular dilatation (b), Group III - arthritis + methanol extract of Vitellaria paradoxa (VPME) 75 mg/kg, shows skin disorganization (fibroblasts and collagen fiber) and cells infiltrations (c), Group IV - arthritis + VPME 150 mg/kg, shows mild edema formation fibroblasts are well-arranged (d), Group V - arthritis + VPME 300 mg/kg, shows mild edema formation and cells organization without vasodilatation (e) and Group VI - arthritis + diclofenac-treated group (f)