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. 2015 Nov;4(4):165–169. doi: 10.5582/irdr.2015.01024

Table 1. Summary of reported distribution, level of expression, and methods of detection of LAT1 in human tumors.

Link to disease Expression Method of detection Ref.
Uterine cervical carcinoma Higher in invasive squamous cell carcinoma than in cervical intraepithelial neoplasia Immunohistochemistry (14,34)
Non-small cell lung cancer Higher in patients with mediastinal lymph node metastases than in those without Immunohistochemistry, quantitative real-time PCR (4,27)
Oral cancer High Immunohistochemistry (22,35,36)
Breast cancer High Immunohistochemistry, quantitative real time PCR, Western blotting (37,38)
Renal cell carcinoma High Quantitative real-time PCR (20)
Esophageal squamous cell carcinoma High Immunohistochemistry (37)
Leukemic High Western blotting (15)
Cholangiocarcinoma High Quantitative real- time PCR (4)
Multiple myeloma High, associated with increased proliferation Immunohistochemistry (39)
Malignant gliomas Higher in infiltrating glioma cells than in cells located in the center of the tumor Immunohistochemistry (13)
Gastric cancer High Quantitative real-time PCR, Western blotting (40)
Prostate cancer High Immunohistochemistry (28,31,41)
Thymic carcinomas High Immunohistochemistry (18)