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Synthesis of the conjugates. Conjugate 3 (PLGA18KDa-PEG3.5KDa-NH2) was used as a main polymer to formulate NC. Conjugate 6 (PLGA18KDa-PEG3.5KDa-NH-DTPA) contained the chelating molecule DTPA to facilitate radiolabeling of the conjugate with radioisotopes.
