Skip to main content
. 2015 Oct 30;11:2038–2056. doi: 10.3762/bjoc.11.221

Table 3.

Metathesis reactions catalysed by Scorpio-type complexes in air.a

Substrateb Productb Solvent (M) Catalyst (mol %) Time (min) Yield (%)c
Inline graphic
29 		Inline graphic
30 		DCM (0.05)
DCM (0.05)
EtOAc (0.1 M)d 		76a (1)
76b (1)
76b (0.2)		 60
30
60		 94
98
>99e
Inline graphic
77 		Inline graphic
78 		DCM (0.05)
DCM (0.05)		 76a (1)
76b (1)		 150
60		 97
96
Inline graphic
46 		Inline graphic
47 		DCM (0.05)
toluene (0.1)f 		76b (1)
76b (0.1)		 20
60		 >98
94
Inline graphic
79 		Inline graphic
80 		DCM (0.05)
toluene (0.1)f 		76b (1)
76b (0.1)		 40
60		 >98
96
Inline graphic
55 		Inline graphic
56 		DCM (0.05)
DCM (0.05)
toluene (0.1)		 76a (1)
76b (1)
76b (0.5)		 45
30
300		 99
<98
92

aReaction conditions: catalyst, nondegassed DCM, reflux, t. bE = COOEt. cIsolated yields after column chromatography. dEthyl acetate is ACS grade solvent, temperature is 40 °C. eConversion determined by GC. fAdded dropwise with a syringe pump [69].