Figure 1.

Effect of saline (sal) or SKF81297 (0.4 and 0.8 mg/kg) injected before the sample phase on novel object recognition after a retention delay of 10 min. (A) Timeline of experiment 1 to illustrate the 10 min retention delay between the sample and the choice phase and the timing of the injections 15 min before the sample phase. (B) Effect of SKF81297 on the first min of exploration of a novel (Nov) and a familiar (Fam) object during the choice phase. *p<0.05, ***p<0.0001, significant difference as compared to familiar object. (C) Choice performance presented as discrimination ratio; stippled line indicates chance. **p<0.001, significantly different from the saline group; ^#p<0.05, ^###p<0.0001 significantly different from chance. Data are shown as a mean±S.E.M (n=12 rats per group).