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. 2015 Aug 12;98(6):1061–1070. doi: 10.1189/jlb.3A0315-102R

Fig. 5. Differential effects of RTD-1 and TACE inhibitor marimastat (MM).

Fig. 5.

(A) THP-1 macrophages were treated with or without LPS (100 ng/ml) in the presence or absence of MM and RTD-1. TNF-α (black bars) and IL-1β (open bars) secreted in the medium were then measured by ELISA. Results are means ± sd from 3 independent experiments. (B) Differentiated THP-1 Dual cells were stimulated with 100 ng/ml LPS and coincubated with the indicated reagents and NF-κB activity was measured relative to control using the Quantiblue assay. Results shown are means ± sd from 3 independent experiments. *P < 0.05 when compared with MM + LPS treatment.