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. 2015 Jul 31;98(6):1003–1013. doi: 10.1189/jlb.4VMA0315-125RR

Figure 4. Staphylococcus aureus biofilm-associated MDSCs inhibit T cell activation in an IL-10-independent manner.

Figure 4.

MDSCs were purified by FACS from infected IL-10 KO and WT mice at d 14 postinfection for T cell proliferation assays at a 1:1 or 5:1 ratio (T cell:MDSC). Results are expressed as the percentage of proliferation with T cells alone (−) and CD3/CD28-stimulated T cells (+) as controls. Results represent 2 independent experiments with significant differences denoted by asterisks (***P < 0.001, ****P < 0.0001; unpaired Student’s t test).