Table 1.
cNST
| Chow/Sham (N=7) |
HFD/Sham (N=8) |
Chow/RYGB (N=3) |
HFD/RYGB (N=8) |
Statistical Significance |
|
|---|---|---|---|---|---|
| Weight (g) | 730±36.3 | 881±45.5 | 507±23.3 | 586±15.8 | D, S |
| Hematocrit | 0.5±0.01 | 0.6±.04 | 0.4±0.02 | 0.4±0.02 | S |
| Blood Glucose (mg/dL) | 197±16.1 | 197±8.4 | 179±28.1 | 195±10.6 | NS |
| Membrane Resistance (mΩ) | 799±47.6 | 790± 38.6 | 945±75.2 | 874±44.3 | NS |
| Resting Membrane Potential (mV) | −50±9.7 | −49±8.1 | −50±8.5 | −51±8.1 | NS |
| Action Potential Amplitude (mV) | 95±1.7 | 93±1.2 | 95±2.0 | 96±1.3 | NS |
| Action Potential Half Width (ms) | 0.9±0.03 | 0.9±0.02 | 0.9±0.03 | 0.9±0.02 | NS |
| Afterhyperpolarization Amplitude (mV) | −37±1.6 | −37±1.1 | −32±1.6 | −37±1.2 | NS |
| TOC + | 62% (44) | 67% (66) | 50% (17) | 62% (52) | χ2, NS |
| TOC − | 38% (27) | 33% (33) | 50% (17) | 38% (32) | |
| AP | 84.7% (61) | 80.4% (82) | 73.2% (30) | 68.6% (59) | χ2, NS |
| cAP | 6.9% (5) | 15.7% (16) | 22.0% (9) | 25.6% (22) | |
| rAP | 8.3% 6) | 3.9% (4) | 4.9% (2) | 5.8% (5) |
N’s in the header column indicate number of animals per group.
Values indicate means ± S.E.M. or proportions expressed as percentages. The numbers of neurons appear in parentheses.
Statistical Significance indicates outcomes of ANOVA or chi-square (χ2) analyses. Significant effects: D , diet, S, surgery, NS, no significant main effects or interactions.
Abbreviations: TOC+ (transient outward current positive neurons); TOC− (transient outward current negative neurons); AP, level of the caudal solitary nucleus at the level of the area postrema; cAP, level caudal to the area postrema; rAP, level rostral to the area postrema