Table 3.
Summary of Mean Values of Clinical Ocular Surface Parameters, Corneal Sensitivity, and Blink Rate in Patients with Tear Dysfunction and Normal Controls
Group | Cochet-Bonnet | AJEa (g) | TBUTb (sec) | K FLc | C LGd | OCT TMHe (mm) | OSDIf | Blink Rate (blinks/min) |
---|---|---|---|---|---|---|---|---|
Normal | 5.45 0.832 | 0.004 ± 0.004 | 9.8 ± 0.633 | 0 | 0 | 330.2 ± 161.7 | 14.25 ± 4.713 | 14 ± 6.481 |
All Tear Dysfunction | 4.906 ± 1.45 | 0.008 ± 0.009 | 3.632 ± 2.06* | 3.303 ± 4.405 | 2.455 ± 2.209* | 309.3 ± 323.4 | 34.53 ± 10.65* | 28.37 ± 16.88 |
Meibomian Gland Disease | 5.7 ± 0.538¶ | 0.006 ± 0.008 | 3.455 ± 1.214* | 3.636 ± 5.065 | 1.455 ± 1.695¶ | 289.5 ± 57.56 | 34.0 ± 11.09* | 18 ± 15.61 |
Aqueous Tear Deficiency | 3.6 ± 1.647*§¥** | 0.012 ± 0.013* | 3.044 ± 1.676* | 6 ± 4.714*§ | 4.3 ± 1.889*§¥** | 171.5 ± 40.98* | 30.20 ± 6.779* | 37.18 ± 17.58* |
Conjunctivo chalasis | 5.333 ± 1.073¶ | 0.007 ± 0.006 | 4.286 ± 2.809* | 0.75 ± 1.055¶ | 1.833 ± 2.038¶ | 486.8 ± 559.7 | 39.0 ± 12.08* | 27.44 ± 14.19* |
Values are mean ± standard deviation (SD).
P values are compared using ANOVA with Tukey post hoc test.
Denotes statistically significance difference (p ≤ 0.05) compared to normal;
denotes statistical significance compared to all subjects;
denotes statistical significance compared to meibomian gland disease;
denotes statistical significance compared to aqueous tear deficiency;
denotes statistical significance compared to conjunctivochalasis.
AJE = Air Jet Esthesiometer;
TBUT = tear break up time;
K FL = corneal fluorescein;
C LG = conjunctival lissamine green;
OCT TMH = optical coherence tomography tear meniscus height;
OSDI = Ocular Surface Disease Index