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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Arthritis Rheumatol. 2015 Dec;67(12):3146–3157. doi: 10.1002/art.39321

Figure 6.

Figure 6

Gene expression in the joints of wildtype and IRF5-deficient mice during active arthritis. Gene expression was analyzed using Nanostring technology on RNA isolated from the joints of C57BL/6 wildtype (WT; n = 4) and IRF5-deficient (IRF5−/−; n = 5) mice 7 days after the i.p. injection of 150 μl of K/BxN serum on day 0 and day 2. Genes that differed between WT and IRF5−/− mice using a threshold statistical significance of p ≤ 0.02 are shown. Samples are arranged by hierarchical clustering and are displayed as a heat map.