. Author manuscript; available in PMC: 2016 Apr 26.

Published in final edited form as: J Biopharm Stat. 2015 May 26;26(3):409–420. doi: 10.1080/10543406.2015.1052475

Table 2.

Varying Variance Model. NF, numerical failure; OOL, out of limits; CP, coverage probability.

Methods		σ = 0.05				σ = 0.08				σ = 0.1
Methods		θ = 0.5	0.8	1	1.2	θ = 0.5	0.8	1	1.2	θ = 0.5	0.8	1	1.2
# of NF	New	0	0	0	0	0	0	0	0	0	0	0	0
# of NF	Trad	993	991	988	995	981	986	998	988	993	988	996	997

# of OOL	New	0	0	0	0	0	0	6	24	0	6	25	76
# of OOL	Trad	0	0	0	0	0	1	1	2	0	1	1	2

CP	New	0.88	0.94	0.93	0.94	0.93	0.95	0.95	0.94	0.94	0.95	0.93	0.94
CP	Trad	0.57	1.00	0.67	0.40	0.79	0.92	.	0.80	0.86	0.91	1.00	.