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. 2015 Sep 9;34(4):753–764. doi: 10.1007/s10555-015-9595-8

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© The Author(s) 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 7 — EPLIN profile in clinical prostate and breast cancer. Immunohistochemical staining (×20 objective magnification) of normal and cancerous a prostate and b breast clinical samples demonstrating EPLIN localisation and expressional differences. c, d Semi-quantitative analysis of EPLIN staining within prostate clinical cohort demonstrates that lower levels of EPLIN staining are associated with cancerous and higher-grade samples. e Within a clinical breast cancer cohort, lower transcript expression of EPLIN is seen in tumour samples compared to normal breast tissue and was associated with a higher grade (f), a poorer patient prognosis (g) and reduced overall survival rates (h). Figure modified from [10, 12]