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Radiopeptide affinity (IC-50 values in nmol/L) profile for somatostatin receptors (SSTR) commonly expressed in NETs
| SSTR2A (nmol/L) | SSTR3 (nmol/L) | SSTR4 (nmol/L) | SSTR5 (nmol/L) | |
|---|---|---|---|---|
| SRS | ||||
| 111In-pentetreotide | 22 | – | – | – |
| SRPET | ||||
| 68Ga-DOTA-TOC | 2.5 | – | – | 73 |
| 68Ga-DOTA-TATE | 0.2 | – | – | – |
| 68Ga-DOTA-NOC | 1.9 | 40 | – | 7.2 |
SSTR somatostatin receptor, SRS somatostatin receptor scintigraphy, SRPET somatostatin receptor positron emission tomography, − low or absence of affinity
