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. 2015 Nov 27;6:247. doi: 10.3389/fneur.2015.00247

Figure 3.

Figure 3

Receiver operating characteristic curve comparison for AD diagnosis in the “discordant CSF Aβ42 values” subpopulation. DeLong et al.’s (1988) method was used to compare the values of the area under the curve (AUC). In the 525 selected patients, accuracy of diagnostic performance was significantly higher for CSF Aβ40 compared to CSF Aβ42/Aβ40 ratio, with 94.7% sensitivity and 91.0% specificity for CSF Aβ40 ≥12,644 ng/L (AUC, 0.969) compared to 76.2 and 58.2%, respectively for CSF Aβ42/Aβ40 ratio ≤0.06 (AUC, 0.700).