Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Nov 27;6:284. doi: 10.3389/fphar.2015.00284

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Yonkunas and Kurnikova.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

(A) Two-dimensional PMF profile for native KcsA M2 bundle, (B) mutant E118A/E120, and (C) mutant E118A/E120A/T112⁺ KcsA M2 bundle shown in a contour plot as a function of reaction coordinates ζ₁ and ζ₂. Each colored contour represents approximately 1 kcal/mol. (D) One-dimensional profile (ζ₁ = ζ₂) of the PMF for the native KcsA M2 bundle, (E) mutant E118A/E120A, and (F) mutant E118A/E120A/T112⁺ KcsA M2 bundle shown in (A–C) as dotted lines.