Table 2.

Body weight change in high-fat diet-induced type 2 DM mice. Mice were provided either normal diet or high-fat diet for 140 days. At day 60, a subset of mice was administered EGb 761 (50 mg/kg, p.o.) or saline every two days for the duration of the experiment. The body weights are shown as mean±SEM of 7 mice. One-way ANOVA followed by Fisher's PLSD test was used for statistical analysis. N, normal diet; H, high-fat diet; E, EGb 761; S, Saline. Statistical significance was found for high-fat diet+saline group versus normal diet+saline group (day 60), high-fat diet+EGb 761 group versus normal diet+EGb 761 group (day 60), high-fat diet+saline group versus normal diet+saline (day 140), high-fat diet+EGb 761 group versus high-fat diet+saline group (day 140). **p <0.01.

Exp. groups	Day 0	Day 60	Day 140
N+S	19.3±0.6	27.2±0.6	33.3±0.7
N+E	18.8±0.5	26.2±0.7	34.1±0.4
H+S	19.2±0.4	31.6±1.1**	45.4±0.9**
H+E	18.5±0.4	31.2±0.9**	40.9±1.1**