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Dynamic behaviors of the HVR in the models 1 and 2 of full-length K-Ras4B-GTP. Backbone superimposition of simulated snapshots sampled at each 25-ns interval over 200 ns simulation to the initial models 1 (A) and 2 (B) of full-length K-Ras4B-GTP in the WT, G12C, G12D, G12V, G13D, and Q61H systems. The locations of mutation sites are colored in red.
