TABLE 3.
Interactions between TCR and NLV peptide in the C25·NLV·HLA-A2, RA14·NLV·HLA-A2, and C7·NLV·HLA-A2 complexes
| Hydrogen bonds | Van der Waals contacts | Hydrogen bonds | Van der Waals contacts | Hydrogen bonds | Van der Waals contacts | |
|---|---|---|---|---|---|---|
| NLV | C25 | C25 | RA14 | RA14 | C7 | C7 |
| N1P | N1P(Nδ2) N29α(Oδ1) | N29α | ||||
| V3P | Y31α | |||||
| P4P | T30α | N29α | P4P(O) G95α(N) | N29α | ||
| T91α | F30α | F30α | ||||
| N992α | Y31α | Y31α | ||||
| G95α | ||||||
| M5P | M5P(O) T100β(Oγ1) | N991α | M5P(Sδ) N96α(N) | Y31α | M5P(Sδ) N96α(N) | Y31α |
| N992α | G95α | I93α | ||||
| N993α | G98β | G95α | ||||
| Gly-99β | G99β | N96α | ||||
| T100β | I100β | W100β | ||||
| N102β | ||||||
| V6P | V6P(O) T100β(N) | G99β | G98β | W100β | ||
| T100β | ||||||
| A7P | T100β | T97β | Q98β | |||
| T101β | G98β | W100β | ||||
| G99β | ||||||
| T8P | T101β | T8P(N) T97β(O) | Q30β | T8P(N) Q98β(Oϵ1) | Q98β | |
| T8P(Oγ1) E30β(O ϵ1) | T97β | T8P(Oγ1) Q98β(Oϵ1) | ||||
| T8P(Oγ1) T97β(O) | ||||||
| T8P(Oγ1) T97β(N) |